A team of researchers, led by Xianghong Zou at the Ohio State University Comprehensive Cancer Center, have discovered that a substance, indole-3-carbinol (I3C), which is produced when eating broccoli and Brussels sprouts, may block the production of cancer cells.“The laboratory and animal study discovered a connection between I3C and a molecule called Cdc25A, which is essential for cell division and proliferation. The research showed that I3C causes the destruction of that molecule and thereby blocks the growth of breast cancer cells.”According to the research, Cdc25A is frequently associated with poor prognoses and can be found in about half of breast cancer patients. Additionally, high levels are often found in cancers of the prostate, liver, esophagus, endometrium and colon, and in non-Hodgkin lymphoma. Furthermore, this molecule has been found in people with Alzheimer's disease.
“For this study, Zou and his colleagues exposed three breast cancer cell lines to I3C. These experiments revealed that the substance caused the destruction of Cdc25A. They also pinpointed a specific location on that molecule that made it susceptible to I3C, showing that if that location is altered (because of a gene mutation), I3C no longer causes the molecule's destruction.”The researchers tested I3C on mice with breast cancer tumors. When I3C is given orally, the tumors reduced in size by up to 65%. However, they also discovered that I3C had no affect on the tumor cells when the Cdc25A molecule had a gene mutation in the specific location.
Consequently, this research suggests that further study is urgently needed as treatment with various dietary supplements may prove to be safe and effective methods of treating cancer and other diseases associated with high levels of Cdc25A before permanent changes to DNA can occur.
How Dietary Supplement May Block Cancer Cells
© www.thehealthnewsblog.com
0 comments:
Post a Comment